Delorme then collaborated with U-M Advanced Genomics core for the RNA sequencing. Nashville, TN. Director of the UNC Microbiome Core Associate Professor of Medicine in the School of Medicine at UNC Chapel Hill Speaker Profile: M. Andrea Azcarate-Peril, Ph. Data Freeze 4, the most current Freeze, was released in July 2021 and contains data from 60,215 genotyped MGI participants. In addition, users will have access to our exclusive pipeline to perform further data analysis. Evan T. Keller, DVM, PhD is a Professor of Urology and Pathology, School of Medicine, University of Michigan. Presented By: NanoString and the BRCF Advanced Genomics Core Spatial genomics and transcriptomics is a rapidly evolving area of research that enables correlation of the expression of tens of thousands of genes and hundreds of proteins with morphological location in a tissue. The team used two U-M core facilities, the Flow Cytometry Core and the Advanced Genomics Core. The Advanced Technology Genomics Core (ATGC) is the primary, "one-stop" genomics core facility for researchers at MD Anderson Cancer Center. Vanderbilt University Medical Center. 9 Chronic Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Arizona, USA. This service is all-inclusive, starting with cells and ending with basic data analysis. Dr. Azcarate-Peril currently conducts research in modulation of the host-associated microbiota by prebiotics and probiotics. —. One NovaSeq run can generate as much as 4TB of raw data. We are a full-service Core, and work closely with our investigators to meet their needs and make their research as successful as possible. One NovaSeq run can generate as much as 4TB of raw data. Initially adopted by the Medical School's Biomedical Research Core Facilities (BRCF) in Fall 2013, Agilent CrossLab iLab Operations Software is a core facility management system designed to support operations for a myriad of types and sizes of centralized labs and shared resource facilities. The Department of Veterans Affairs, VA Ann Arbor Medical Center VISN 10,2215 Fuller Road, Ann Arbor MI 48105, in accordance with FAR 13.106-1(b), intends to request quota AJ11--Advanced Genomics Core UofM - Dr. Mody CubeWorks was founded by pioneering researchers at the University of Michigan, and the company uses core technology stemming from 10+ years of ultra-low power VLSI circuit research that enables ultra-low power wireless sensors with unprecedented form factors and battery life. Libraries were sequenced using 150 paired end NovaSeq 6000 (Illumina). Both training programs are ACGME-accredited and are based in the Department of Pediatrics. Spatial Applications can help both research and clinical development . Olivia Koues, PhD advanced-genomics@umich.edu BRCF Bioinformatics Core assists with the experimental design, workflow development, and analysis of next-generation sequencing data. They hope that the Advanced Genomics Core will remain operational and will be able to perform sequencing of their samples. IMC uses antibodies conjugated to heavy metals to detect markers in a manner analogous to immuno-histochemistry or immunofluorescence microscopy. Biostatistics 830. Primary Contact for Histology: Chelsea Decker. 734-615-3758. bi-equipment@umich.edu. During the remainder of the week, the lab will prepare a large batch of experimental samples, which will be submitted for high throughput sequencing at the U-M Advanced Genomics Core. This work is supported by funding from the University of Michigan, including the MCubed program, Department of Cell and Developmental Biology's IDEA Awards in Stem Cell Biology, and the MTRAC program. We thank the University of Michigan Advanced Genomics Core for performing the targeted capture sequencing and 10X linked-read sequencing. Leadership Olivia I. Koues, Ph.D. - Managing Director Thomas E. Wilson, M.D. The University of Michigan Bru-seq Lab is a core facility that provides nascent RNA sequencing services for samples prepared using the Bru-seq suite of techniques. We also thank Dr. Tom Wilson for discussions of the data. The Advanced Genomics Core (AGC), part of the Biomedical Research Core Facilities within the Medical School Office of Research, provides high-quality, low-cost next generation sequencing analysis for research clients on a recharge basis. Course Description: HG541, Molecular Genetics, is a course that explores how the information content of the DNA genome is (i) organized, propagated, and altered, and (ii) functionally expressed by regulated transcription into RNA - the core molecular properties and processes of genetic systems that underlie all further investigations of organismal, clinical, and . Its goal is to use state-of-the-art instrumentation and innovative technical expertise in order to provide investigators with the highest quality genomic data from a comprehensive range of genomic services in a timely manner. RNA concentration and quality were determined and ribosomal depleted mRNA libraries were prepared by the University of Michigan Advanced Genomics Core. Join us for an engaging week of presentations from a diverse group of scientists and hear about the latest advancements from 10x Genomics in single cell and spatial genomics. The Center is developing multiple collaborative labs (CoLabs), technology hubs that facilitate microbiome research projects. The authors acknowledge the Cardiovascular Health Improvement Project, Michigan Genomics Initiative, Precision Health at the University of Michigan, and the University of Michigan Medical School Central Biorepository, and the University of Michigan Advanced Genomics Core for providing data and biospecimen storage, management, processing, and . The Advanced Genomics Core mission is to facilitate research in cutting-edge fields of genetics and genomics by implementing complex technologies. Biostatistics 866. Visit the Website / More Info. The University of Michigan Rogel Cancer Center supports and maintains a state-of-the-art histology and immunohistochemistry laboratory using automated instruments. Sarah Spanninga, PhD. Each program utilizes the combined clinical genetics services, basic science research and education . He observed that, after sleep deprivation, there was a significant increase in abundance of a type of RNA transcripts known to be present specifically in interneurons that express the neuropeptide somatostatin as well as the inhibitory neurotransmitter GABA. The team used two U-M core facilities, the Flow Cytometry Core and the Advanced Genomics Core. University of Michigan Researchers and External Researchers Visit Core Website Core Summary The University of Michigan Biomedical Research Core Facilities (BRCF) Advanced Genomics Core (AGC) provides high-quality, low-cost advanced genomic analysis for research clients on a recharge basis. Delorme then collaborated with U-M Advanced Genomics core for the RNA sequencing. GeoMx DSP Data Analysis Software Overview: Prajan Divakar, PhD, Sr. The AGC is one of the first academic core facilities to optimize this exciting and powerful instrument, that is about the size of a large laser printer. Lab Number: (734) 647-3261. One NovaSeq run can generate as much as 4TB of raw data. Medical School COVID-19 Research Operations. The University of Michigan (U-M) Training Program in ELSI Research, funded by the National Institutes of Health, seeks to prepare the next generation of ELSI . D. is Associate Professor of Medicine in the School of Medicine at UNC Chapel Hill. College of Education, Health, and Human Services (Dearborn) 4 people. Bachelor's Degree. We serve researchers from the University of Michigan, and other institutions in the United States and around the world. College of Literature, Science, and the Arts 235 people | 101 documents. Figure 1. The Core occupies approximately 10,000 square feet of laboratory space in the North Campus Research Complex, with 22 highly-trained individuals on staff to help you. On the cutting-edge of research at U-M is the Advanced Genomics Core's Illumina NovaSeq 6000 sequencing platform. 28,251 (≈ 47%) of participants are male and 31,964 (≈ 53%) are female. GeoMx Project Requirements: University of Michigan Advanced Genomics Core; April 14th: GeoMx Data Analysis Workshop. Users can request services for these four assays: BruUV-seq . EECS 409-001: Each semester MIDAS hosts weekly seminars featuring data science leaders from industry and academia. View the seminar schedule. BRCF Advanced Genomics Core (AGC) provides high-quality, low-cost advanced genomic analysis on a recharge basis. This work is supported by funding from the University of Michigan, including the MCubed program, Department of Cell and Developmental Biology's IDEA Awards in Stem Cell Biology, and the MTRAC program. Presented by 10x Genomics and University of Michigan Advanced Genomics Core Deep insights into tumor biology, developmental biology, and other biological processes and disease states require a comprehensive view of gene expression patterns and their corresponding epigenetic regulation at single cell resolution. The ideal candidate will have skills in one or more of the following areas: bioinformatics using second or third generation sequencing data, comparative genomics, advanced fluorescence or electron microscopy, molecular biology such as cloning, and working with living cultures. For sorting of fibroblasts . Paper cited: Michki et al., Over the past decade, the University of Michigan has become a leader in natural product sciences. COVID-19 vaccinations, including boosters when eligible, are required for all University of Michigan students, faculty and staff across all campuses, including Michigan . Data Freeze 4, the most current Freeze, was released in July 2021 and contains data from 60,215 genotyped MGI participants. The University of Michigan Medical School began in the year 1850 with five faculty members, 90 students, and five physicians seeking additional training. The University of Michigan Skin Biology and Diseases Resource-based Center (UM-SBDRC) will accelerate the science and innovation of the Center's members and the broader community of cutaneous researchers by supporting innovative basic research in cutaneous biology and facilitating its translation to clinical practice. Hosted by 10x Genomics and The University of Michigan Advanced Genomics Core. Chief among these is "next-generation" sequencing (NGS), which has revolutionized research in virtually all biological fields in the past decade. Coordination with the Advanced Genomics Core for submission of samples and communication with the core regarding anticipated sample flow to ensure adequate supplies; . Illumina-ready Libraries for NGS. 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